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Low Dose Naltrexone


Low Dose Naltrexone : this service is for clients who are not current Zuza’s Way patients. 


Low Dose Naltrexone Delivered to you!

Now it is easier than ever to get a prescription for LDN!

1. Book Video Consultation 
2. Fill out intake paperwork
3. Meet with Practitioner
4. Arrange shipment from pharmacy

What is Low Dose Naltrexone? 

Naltrexone is a medication that was approved in the 1980s by the FDA to treat drug and alcohol addiction.  It works by blocking opioid receptors.  It was found that at much lower doses than those used to treat addiction, it could have a positive effect on the immune system and potentially help relieve symptoms of many common disorders.

To read more about LDN, visit AND

What is LDN used for? 

Naltrexone is currently only FDA approved for Alcoholism and Opioid Addiction.

However, like many medications, Naltrexone at low doses is used “off-label” for many conditions.

LDN has been reported helpful with:

  • Fibromyalgia/Chronic Fatigue Syndrome

  • Autoimmune conditions (Colitis, Lupus, Rheumatoid Arthritis, etc…)rders

  • Cancers of many types

  • Infectious diseases (HIV, Lyme, etc…)

  • Anxiety and Depression

  • Osteoarthritis

  • Weight loss

  • Skin disorders

For a more comprehensive list, visit AND

How is LDN used? 

LDN is taken by mouth – usually either capsule or liquid form. Dosing ranges from 0.5 to 9mg per day. The most common effective dose is 4.5mg, but can vary from person to person. It is recommended to be taken at bedtime, but can also be effective if taken during the day.

Who can get LDN? 

Must be 18 years and older (or 12 and older if accompanied by a parent or guardian)

Video consultation is available to residents of states where our doctors are licensed.

NOW AVAILABLE: All 50 States

How do refills work? 

Once you become a patient you will get instructions on refills.  Refills can be filled through email and cost $49.99 


Low Dose Naltrexone Studies: 

Crohn’s Disease:  Paulides E, Lie MRKL, van der Woude CJ. Low-dose naltrexone for the induction of remission in patients with mild to moderate Crohn's disease: protocol for the randomised, double-blinded, placebo-controlled, multicentre LDN Crohn study. BMJ Open. 2022 Apr 8;12(4):e058358. doi: 10.1136/bmjopen-2021-058358. PMID: 35396307; PMCID: PMC8996009.

Leonard Weinstock, EFFICACY OF LOW DOSE NALTREXONE IN PATIENTS WITH CROHN’S COLITIS AND ILEITIS, Inflammatory Bowel Diseases, Volume 28, Issue Supplement_1, February 2022, Pages S106–S107,

Ulcerative Colitis: Lie MRKL, van der Giessen J, Fuhler GM, de Lima A, Peppelenbosch MP, van der Ent C, van der Woude CJ. Low dose Naltrexone for induction of remission in inflammatory bowel disease patients. J Transl Med. 2018 Mar 9;16(1):55. doi: 10.1186/s12967-018-1427-5. PMID: 29523156; PMCID: PMC5845217.

Hashimotos disease:

Skin Disorders:



Couto RD, Fernandes BJD. Low Doses Naltrexone: The Potential Benefit Effects for its Use in Patients with Cancer. Curr Drug Res Rev. 2021;13(2):86-89. doi: 10.2174/2589977513666210127094222. PMID: 33504322.

Anxiety/ Depression:

Low Dose Naltrexone 

Welcome to your LDN healing journey.  We are excited to be able to prescribe this medication and encourage you to work with US or another well versed practitioner on LDN. 


Standard dosing instructions*

Begin with 1.5 mg each evening, approximately 1 hour before bed. Stay at this dose for two weeks. Every two weeks, add a dose of 1.5 mg. Continue adding until you find the maintenance dose that is best suited to you.

Week 1 + 2: 1.5mg daily
Week 3 + 4: 3mg daily
Week 5 + 6: 4.5 mg daily

If you are beginning at a lower dose, the titration schedule remains the same- you increase by your beginning dose every two weeks until you find your optimal dose.

Keeping a symptom journal will help you to find the best dose. On day one, write down your top 3-5 symptoms and rate them on a scale of 1-10. Twice a week while increasing the naltrexone, rate your symptoms. When you find 100% symptom relief OR plateau at symptom relief, you have found your maintenance dose.

If you experience side effects such as nausea, headache, gas, diarrhea, insomnia, heightened anxiety, or vivid dreams or nightmares, they should be mild to moderate and should self-regulate in 3-5 days. If they do don’t go away by day 5, this indicates the 1.5 mg dose is too high for you to start with, and you should halve your dose to 0.75mg. In this case you will titrate more slowly, increasing every two weeks by 0.75 mg. If the only side effects you experience are insomnia or vivid dreams or nightmares, you may switch to taking the LDN during the day rather than at night.

*These highlights are based on default dosing. Actual dosing might differ significantly.

Low Dose Naltrexone Side Effects: 

LDN is well tolerated in most patients and limited further when a patient is started on a start low and go-slow method. This means the patient should be started at a low dose and titrated up slowly. When side effects occur, they are usually mild and include:

  • Sleep disturbances

  • Mild headache/GI effects - consider switching to liquid sublingual LDN to bypass GI tract

  • Mild agitation

  • Nausea

It has been found in patients that experienced side effects, that they can be stopped by decreasing the dose by half for 2-3 days, and then continuing with titration again.

*if you have side effects contact your medical practitioner or send us a message on the portal (fee’s may apply) 

Refills $49.99 

We wanted to make refills easy for you - all you have to do is request a refill for LDN through the portal and it will be refilled.  If you feel you are not tolerating your dose well or have questions you can send us a message with the refill request. 

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